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Phenelfamycin A CAS NO 118498-91-2


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CAS No.:118498-91-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Phenelfamycin A is a member of the elfamycin class of antibiotics, known for its potent antibacterial activity against Gram-positive bacteria. This compound is valued in research and development for its unique mechanism of action, which involves the inhibition of protein synthesis, making it a critical tool for studying bacterial resistance and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on antimicrobial discovery and mechanism-of-action studies.

Application

  • Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of new antibacterial agents.
  • Mechanistic Studies: Used in microbiological and biochemical research to investigate the inhibition of bacterial protein synthesis and pathways to antibiotic resistance.
  • Analytical Standard: Employed as a high-purity calibrant in quality control (QC) laboratories for the identification and quantification of elfamycin compounds via HPLC, LC-MS, or other analytical methods.
  • Biotechnology Applications: Utilized in cell culture and fermentation process studies to select for or study specific bacterial strains.

Basic Information

Product Name Phenelfamycin A
CAS No. 118498-91-2
Molecular Formula C42H61NO14
Molecular Weight 803.93 g/mol
Synonyms Phenelfamycin; Antibiotic A 35512; A-35512; Phenelfamycin A1; Elfamycin antibiotic; (2S,3S,4S,5S,6R)-6-[[(2S,3S,4S,6S)-4,6-Dimethyl-3-[[(2R,3R,4R,5S,6S)-5-[(2S,3S,4S,6S)-4,6-dimethyl-3-(methylamino)oxan-2-yl]oxy-3,4,6-trimethyloxan-2-yl]oxy]-2-(methylamino)oxan-2-yl]oxy]-3,4,5-trimethyloxane-2-carboxylic acid
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Quality Control

Our Phenelfamycin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. The container should be kept tightly sealed in a dry, well-ventilated area.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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