Description

Tazarotene is a synthetic retinoid derivative specifically designed for targeted therapeutic action. Its primary value lies in its ability to modulate cell differentiation and proliferation, making it a critical active pharmaceutical ingredient (API). This compound is essential for manufacturers in the global pharmaceutical industry developing topical treatments for dermatological conditions.

Application

• Active Pharmaceutical Ingredient (API) in prescription topical gels and creams for the treatment of acne vulgaris.
• Key therapeutic agent in formulations targeting plaque psoriasis to reduce scaling and thickness.
• Primary component in dermatological preparations for mitigating fine facial wrinkles and skin discoloration associated with photodamage.
• Research chemical in preclinical and clinical studies exploring retinoid pathways and new dermatological applications.
• Reference standard for quality control laboratories in pharmaceutical manufacturing and regulatory testing.
• Raw material for compounding pharmacies requiring high-purity retinoids for specialized formulations.

Basic Information

Product Name	Tazarotene
CAS No.	118292-40-3
Molecular Formula	C21H21NO2S
Molecular Weight	351.46 g/mol
Synonyms	Ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]nicotinate; AGN 190168; Zorac; Tazorac; Tazaroten; Tazaroteno; Tazarotène
EINECS	Contact for details

Quality Control

Our Tazarotene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.