Description

1-(2-(3-Iodo-4-Azidophenyl)Ethyl)-4-(3-(Trifluoromethyl)Phenyl)Piperazine is a specialized, high-value organic building block designed for advanced research and development. This compound is critical for applications requiring precise molecular architecture, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and academic researchers focused on medicinal chemistry and chemical biology.

Application

• Pharmaceutical Research: Key intermediate in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and receptor-binding studies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique trifluoromethyl and azido functional groups.
• Chemical Biology & Proteomics: The azido group enables bioorthogonal "click chemistry" reactions (e.g., CuAAC) for labeling, probing, and modifying biomolecules.
• Agrochemical Development: Serves as a precursor in the design of novel active ingredients with enhanced biological activity and environmental stability.
• Material Science: Potential building block for advanced functional materials, including polymers and liquid crystals, leveraging its aromatic and piperazine structure.
• Radiopharmaceuticals: The iodine atom provides a potential site for radioisotope labeling (e.g., I-125) for diagnostic imaging or therapeutic applications.

Basic Information

Product Name	1-(2-(3-Iodo-4-Azidophenyl)Ethyl)-4-(3-(Trifluoromethyl)Phenyl)Piperazine
CAS No.	118249-08-4
Molecular Formula	C19H18F3IN4
Molecular Weight	486.18 g/mol
Synonyms	1-[2-(3-Iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine; 4-[3-(Trifluoromethyl)phenyl]-1-[2-(3-iodo-4-azidophenyl)ethyl]piperazine; N-(2-(3-Iodo-4-azidophenyl)ethyl)-N'-(3-(trifluoromethyl)phenyl)piperazine; 118249-08-4; 3-Iodo-4-azido-N-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)aniline
EINECS	Contact for details

Quality Control

Our 1-(2-(3-Iodo-4-Azidophenyl)Ethyl)-4-(3-(Trifluoromethyl)Phenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This compound is strictly light-sensitive and hygroscopic; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.