Description

Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 3-(1-Methylethyl)- (9Ci) is a highly functionalized bicyclic acid chloride derivative, serving as a critical building block for introducing a rigid, three-dimensional bicyclo[2.2.2]octane scaffold into target molecules. This compound is valued for its ability to impart unique steric and electronic properties, enabling the synthesis of advanced materials and bioactive compounds with tailored performance. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, lipophilic frameworks to modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the bicyclic structure can enhance stability and biological activity.
• Material Science Precursor: Employed in the synthesis of specialty polymers, dendrimers, and liquid crystals, where its geometry influences material properties like thermal stability and mesophase behavior.
• Chemical Biology Probe Development: Acts as a coupling agent for attaching reporter tags or affinity labels to biomolecules or surfaces via amide bond formation.
• Catalyst and Ligand Synthesis: Serves as a precursor for creating novel chiral ligands or organocatalysts with a sterically demanding core.
• Academic and Industrial R&D: A versatile tool for methodological studies and exploring new chemical space in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 3-(1-Methylethyl)- (9Ci)
CAS No.	118208-00-7
Molecular Formula	C12H17ClO
Molecular Weight	212.72 g/mol
Synonyms	3-Isopropylbicyclo[2.2.2]octane-2-carbonyl chloride; 3-(1-Methylethyl)bicyclo[2.2.2]octane-2-carbonyl chloride; 3-Isopropyl-2-bicyclo[2.2.2]octanecarbonyl chloride; 2-Carbonyl chloride-3-isopropylbicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-2-carbonyl chloride, 3-isopropyl-; 3-Isopropylbicyclo[2.2.2]octan-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 3-(1-Methylethyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including NMR, HPLC, and GC to verify specifications, ensuring the material meets the exacting standards required for pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.