Description

2',3'-Dideoxy-N(6)-Cyclohexyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and reference standard in the synthesis of novel therapeutic agents, particularly those targeting viral and enzymatic pathways. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug discovery and nucleotide chemistry.

Application

• Antiviral Research: Key intermediate in the synthesis and study of nucleoside reverse transcriptase inhibitors (NRTIs) for potential antiviral therapies.
• Biochemical Tool: Used as a substrate or inhibitor in enzymatic assays to study adenosine deaminase and related enzyme kinetics.
• Medicinal Chemistry: Serves as a versatile scaffold for the design and development of novel adenosine receptor ligands and other small-molecule drugs.
• Process Development: Employed as a reference standard and starting material in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in nucleotide biochemistry, metabolic pathways, and drug resistance mechanisms.

Basic Information

Product Name	2',3'-Dideoxy-N(6)-Cyclohexyladenosine
CAS No.	118191-22-3
Molecular Formula	C16H21N5O3
Molecular Weight	331.37 g/mol
Synonyms	N6-Cyclohexyl-2',3'-dideoxyadenosine; ddAdoC; 2',3'-Dideoxy-N6-cyclohexyladenosine; Cyclohexyl-ddA; 9-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]-N-cyclohexyl-9H-purin-6-amine
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-N(6)-Cyclohexyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.