Description

3-Methyl-5-(2-Iodovinyl)-2'-Deoxyuridine is a halogenated nucleoside analogue of significant interest in medicinal chemistry and life science research. This compound matters as a key synthetic intermediate and a potential antiviral or anticancer agent precursor, offering a unique structural motif for probing biological mechanisms. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the development of novel therapeutics, particularly for targeting viral DNA polymerases and studying nucleoside metabolism.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to thymidine kinase and DNA polymerase activity.
• Antiviral Agent Development: Investigated for its potential activity against herpesviruses (HSV) and other DNA viruses due to its modified nucleoside structure.
• Radiopharmaceutical Precursor: The iodine atom provides a handle for radiolabeling (e.g., with I-125 or I-131) for diagnostic imaging or targeted radiotherapy research.
• Medicinal Chemistry Probe: Utilized to study structure-activity relationships (SAR) in the design of modified nucleosides with enhanced therapeutic profiles.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	3-Methyl-5-(2-Iodovinyl)-2'-Deoxyuridine
CAS No.	118068-34-1
Molecular Formula	C12H13IN2O5
Molecular Weight	392.15 g/mol
Synonyms	5-(2-Iodovinyl)-3-methyl-2'-deoxyuridine; 3-Methyl-5-(2-iodovinyl)-2'-deoxyuridine; 5-(2-Iodovinyl)-3-methyl-2'-deoxyuridine; 3-Methyl-5-(2-iodovinyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; IVdUrd; 3-Me-5-IVdU; 3-Methyl-5-(2-iodovinyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(2-Iodovinyl)-2'-Deoxyuridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.