Description

Rabeprazole Sodium is a proton pump inhibitor (PPI) API used to suppress gastric acid production. It is a critical active pharmaceutical ingredient for the formulation of effective anti-ulcer and gastroesophageal reflux disease (GERD) medications. This compound is essential for pharmaceutical manufacturers producing solid oral dosage forms, such as enteric-coated tablets and capsules. Its high purity and consistent quality are paramount for ensuring the safety and efficacy of the final drug product.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for treating acid-related disorders.
• GERD Treatment: Formulation of drugs for gastroesophageal reflux disease, providing long-lasting acid suppression.
• Peptic Ulcer Therapy: Key component in medications for healing and preventing duodenal and gastric ulcers.
• Zollinger-Ellison Syndrome: Used in formulations to manage pathological hypersecretory conditions.
• Helicobacter pylori Eradication: Part of combination therapy regimens for H. pylori infection.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded rabeprazole drugs.
• Clinical Research: Serves as a reference standard or raw material in pharmaceutical R&D and bioavailability studies.

Basic Information

Product Name	Rabeprazole Sodium
CAS No.	117976-90-6
Molecular Formula	C18H20N3NaO3S
Molecular Weight	381.42 g/mol
Synonyms	Rabeprazole Sodium Salt; Sodium Rabeprazole; Pariprazole Sodium; LY307640 sodium; E3810 sodium salt; 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt; (RS)-Rabeprazole Sodium
EINECS	Contact for details

Quality Control

Our Rabeprazole Sodium is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to ensure full traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 5.0%
Related Substances (HPLC)	Total impurities: NMT 1.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%
pH (1% Solution)	9.0 - 11.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.