Description

n-Boc-2-Azidoethylamine is a versatile bifunctional organic building block, featuring both a protected amine (Boc) and a reactive azide group. This compound is essential for the synthesis of complex molecules via click chemistry, particularly in the construction of bioconjugates and pharmaceutical intermediates. It is a critical reagent for researchers and manufacturers in medicinal chemistry, chemical biology, and materials science who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring triazole linkages.
• Bioconjugation & Click Chemistry: Used in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to label biomolecules, create antibody-drug conjugates (ADCs), and develop diagnostic probes.
• Peptide & Protein Modification: Enables site-specific functionalization of peptides and proteins by introducing azide handles for subsequent ligation.
• Polymer & Materials Science: Serves as a monomer or cross-linker for creating functional polymers, hydrogels, and smart materials with tailored properties.
• Chemical Biology Probes: Integral for synthesizing activity-based probes and affinity tags to study enzyme function and protein interactions.
• Agrochemical Research: Used in the discovery and development of novel crop protection agents and agrochemicals.

Basic Information

Product Name	n-Boc-2-Azidoethylamine
CAS No.	117861-38-8
Molecular Formula	C7H14N4O2
Molecular Weight	186.21 g/mol
Synonyms	2-Azidoethylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(2-Azidoethyl)carbamate; 1-Azido-2-[(tert-butoxycarbonyl)amino]ethane; Boc-Azidoethylamine; N-(tert-Butoxycarbonyl)-2-azidoethylamine; N-Boc-2-Azidoethylamine; N-(2-Azidoethyl)carbamic Acid tert-Butyl Ester; Boc-NH-CH2-CH2-N3
EINECS	Contact for details

Quality Control

Our n-Boc-2-Azidoethylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to the azide functionality, handle and store with appropriate safety precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.