Description

Colabomycin A CAS NO 117778-57-1 is a specialized antibiotic compound belonging to the class of ansamycins. This product matters for its significant biological activity, particularly as a potent inhibitor of bacterial RNA polymerase, making it a valuable tool in microbiological and pharmacological research. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the discovery of novel antimicrobial agents and the study of bacterial transcription mechanisms.

Application

• Antimicrobial Research: Serves as a key reference standard and active agent in studies targeting Gram-positive bacteria and mycobacteria.
• Mechanistic Studies: Used to investigate the inhibition of bacterial DNA-dependent RNA polymerase and elucidate transcription pathways.
• Pharmaceutical Development: Acts as a lead compound or intermediate in the discovery and synthesis of new antibiotic candidates.
• Biochemical Assays: Employed in high-throughput screening and in vitro assays to evaluate antibacterial potency and mechanism of action.
• Academic Research: Utilized in university and institutional labs for microbiological and molecular biology research projects.

Basic Information

Product Name	Colabomycin A
CAS No.	117778-57-1
Molecular Formula	C₃₉H₄₈N₂O₁₁
Molecular Weight	720.81 g/mol
Synonyms	Colabomycin A; Antibiotic C 14919; C-14919; Ansamycin antibiotic C 14919; (2S,4aR,5R,6S,7S,8R,9S,11aR,11bS)-5,6,7,8,9,11b-Hexahydro-2,4a,5,7,8,9,11a,11b-octahydroxy-6-methoxy-4a,9,11b-trimethyl-10-oxo-4H-naphtho[2,1-b]pyrano[3,2-e][1,4]dioxacyclotetradecine-12-carboxamide
EINECS	Contact for details

Quality Control

Our Colabomycin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Assay available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.