Description

n-Cyclopentyl-5'-Adenylic Acid is a chemically modified nucleotide analog, specifically an adenosine monophosphate derivative with a cyclopentyl substituent. This structural modification is of significant interest for its potential to modulate biological activity and enhance metabolic stability compared to its parent compound. It serves as a critical building block and research chemical for pharmaceutical R&D, particularly in the development of nucleotide-based therapeutics, enzyme inhibitors, and biochemical probes. Key industries that utilize this specialized compound include biotechnology, academic research, and contract development and manufacturing organizations (CDMOs) focused on novel drug discovery.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel antiviral or anticancer nucleotide analog prodrugs.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphorylases, and adenylate cyclases.
• Proteomics & Molecular Biology: Acts as a precursor for labeled nucleotides used in assay development and diagnostic applications.
• Medicinal Chemistry: Provides a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• API Development: Investigated as a potential active pharmaceutical ingredient (API) in early-stage drug development programs.
• Life Science Reagents: Incorporated into high-purity reagents and kits for cellular signaling pathway analysis.

Basic Information

Product Name	n-Cyclopentyl-5'-Adenylic Acid
CAS No.	117778-38-8
Molecular Formula	C15H21N5O7P
Molecular Weight	414.33 g/mol
Synonyms	Cyclopentyl-AMP; 5'-O-(Cyclopentyl)adenosine monophosphate; Adenosine-5'-(cyclopentyl dihydrogen phosphate); 9-[(2R,3R,4S,5R)-5-[(Cyclopentyloxy)phosphonooxy]-3,4-dihydroxyoxolan-2-yl]-6-aminopurine; cPent-AMP; N-Cyclopentyladenosine 5'-monophosphate
EINECS	Contact for details

Quality Control

Our n-Cyclopentyl-5'-Adenylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.