Description

Thevetoside is a potent cardiac glycoside derived from plants of the *Thevetia* genus. This high-purity compound is valued for its specific biological activity, making it a critical reference standard and research material. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and manufacturers of fine chemicals for pharmacological studies and analytical method development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and assay calibration in drug development and manufacturing.
• Biochemical Research: Serves as a key reagent in cardiovascular research, particularly in studies investigating the mechanisms of cardiac glycosides and sodium-potassium ATPase inhibition.
• Natural Product Isolation & Analysis: Employed as a benchmark in the isolation, purification, and analytical characterization (e.g., HPLC, LC-MS) of related glycosides from plant extracts.
• Academic & Clinical Studies: Facilitates in-vitro and ex-vivo studies to explore structure-activity relationships, toxicity profiles, and potential therapeutic applications of cardiac-active compounds.
• Fine Chemical Synthesis: Acts as a sophisticated starting material or intermediate for the semi-synthesis of novel derivatives with modified pharmacological properties.

Basic Information

Product Name	Thevetoside
CAS No.	117743-32-5
Molecular Formula	C₄₂H₆₆O₁₈
Molecular Weight	858.96 g/mol
Synonyms	Thevetin B; Thevetoside; 3'-O-Methylnerifolin; Cerberoside; 2'-O-Acetylthevetin B; Thevetia glycoside B; NSC 400071; (3β,5β)-3-[(O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
EINECS	Contact for details

Quality Control

Every batch of Thevetoside CAS NO 117743-32-5 is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.