Description

2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbonyl chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound matters because it serves as a critical building block for introducing the unique 2-methyl-4-(trifluoromethyl)thiazole moiety into target molecules, a structure valued for its potential to modulate physicochemical and biological properties. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl-thiazole group can enhance activity and environmental stability.
• Material Science Research: Employed in the development of specialty chemicals, functional materials, and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical manufacturing and scale-up projects for clients.
• Chemical Biology Probes: Useful for creating labeled compounds or molecular probes for biochemical and pharmacological research.

Basic Information

Product Name	2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbonyl chloride
CAS No.	117724-64-8
Molecular Formula	C6H3ClF3NOS
Molecular Weight	229.60 g/mol
Synonyms	5-(Chlorocarbonyl)-2-methyl-4-(trifluoromethyl)thiazole; 2-Methyl-4-trifluoromethyl-1,3-thiazole-5-carbonyl chloride; 2-Methyl-4-(trifluoromethyl)thiazole-5-carbonyl chloride; 4-(Trifluoromethyl)-2-methyl-1,3-thiazole-5-carbonyl chloride; 1,3-Thiazole-5-carbonyl chloride, 2-methyl-4-(trifluoromethyl)-; MFCD11871116
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbonyl chloride is manufactured under controlled conditions to ensure batch-to-batch consistency and a typical purity of 97% (by HPLC/NMR). Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.