Description

Pradimicin A CAS NO 117704-65-1 is a naturally occurring antifungal antibiotic belonging to the benzo[a]naphthacenequinone class. This compound is of significant interest for its unique carbohydrate-binding lectin-like activity, which disrupts fungal cell membrane integrity. It serves as a critical reference standard and research tool for pharmaceutical R&D, microbiology, and antifungal discovery programs targeting resistant pathogens.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis in method development, validation, and quality control of antifungal drug substances and products.
• Antifungal Mechanism Research: A key tool for studying novel modes of action against Candida, Aspergillus, and other pathogenic fungi, particularly for investigating membrane-targeting agents.
• Biochemical Research: Employed in studies of carbohydrate-protein interactions and lectin-like behavior due to its specific binding to mannose residues on microbial surfaces.
• Microbiology & Antimicrobial Discovery: Serves as a lead compound or comparator in high-throughput screening assays to discover new antifungal agents with improved efficacy and safety profiles.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research into fungal biology, resistance mechanisms, and host-pathogen interactions.

Basic Information

Product Name	Pradimicin A
CAS No.	117704-65-1
Molecular Formula	C₆₁H₇₇N₃O₂₁
Molecular Weight	1184.28 g/mol
Synonyms	BMY-28864; Antibiotic BMY 28864; Pradimicin; Pradimicin A, BMY-28864; Benzo[a]naphthacenequinone antibiotic; (1S,3S,12S,14R,15R,16R,32S,33R,36S,37R,41R,43S,44R,45S,46R)-33,36,41,43,44,45-Hexahydroxy-15,16,46-trimethoxy-14-methyl-8,22-dioxo-7,9,21,23-tetraoxa-8lambda5,22lambda5-diazaheptacyclo[23.22.2.23,6.210,13.216,19.226,44.032,46]hexatetraconta-2,4,6(46),10,12,16,18,25,27,29,31,34,36,38,40-pentadecaene-1,3,12,37-tetrayl tetraacetate
EINECS	Contact for details

Quality Control

Our Pradimicin A is produced and handled under strict quality management protocols to ensure identity, purity, and stability for research use. Each batch is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm structure and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to support regulatory submissions and ensure experimental reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Yellow to Orange Powder
Identification (HPLC)	Conforms to Reference Standard
Identification (MS)	Conforms to Structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.