Description

5-(1-Propynyl)-2'-Deoxycytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of oligonucleotides and probes used in molecular biology and therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antiviral agents, anticancer therapies, and diagnostic tools.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used as a modified monomer for constructing labeled or functionalized DNA/RNA strands for research and diagnostics.
• Biochemical Research: Employed in studies investigating DNA replication, repair mechanisms, and enzyme-substrate interactions.
• Probe Development: Acts as a component in the creation of fluorescent or affinity-tagged nucleotide probes for genomic and cellular assays.
• Antisense Technology: Incorporated into antisense oligonucleotides to modulate gene expression for therapeutic discovery.

Basic Information

Product Name	5-(1-Propynyl)-2'-Deoxycytidine
CAS No.	117693-24-0
Molecular Formula	C12H15N3O4
Molecular Weight	265.26 g/mol
Synonyms	5-(1-Propynyl)deoxycytidine; 2'-Deoxy-5-(1-propynyl)cytidine; 5-Prop-1-yn-1-yl-2'-deoxycytidine; dC(Prop) (abbreviation); 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-(1-propynyl)-2(1H)-pyrimidinone; 5-(Prop-1-yn-1-yl)-2'-deoxycytidine; 5-Propynyl-2'-deoxycytidine
EINECS	Contact for details

Quality Control

Our 5-(1-Propynyl)-2'-Deoxycytidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch to document compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.