Description

2H-1,2-Oxazine-2-Carbonyl Chloride, 3,6-Dihydro-4-Methyl- (9Ci) is a specialized heterocyclic building block and reactive intermediate. This compound is valued for its role as a versatile acylating agent in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing the oxazine heterocycle.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic motifs.
• Fine Chemical Production: Serves as a reactive intermediate in the custom synthesis of complex, high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry and organic synthesis laboratories.
• Peptide Mimetics & Conjugate Chemistry: The carbonyl chloride functionality enables its use in coupling reactions to create amide bonds, useful in designing peptide-like compounds or bioconjugates.

Basic Information

Product Name	2H-1,2-Oxazine-2-Carbonyl Chloride, 3,6-Dihydro-4-Methyl- (9Ci)
CAS No.	117593-03-0
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	4-Methyl-3,6-dihydro-2H-1,2-oxazine-2-carbonyl chloride; 3,6-Dihydro-4-methyl-2H-1,2-oxazine-2-carbonyl chloride; 4-Methyl-2H-1,2-oxazine-2-carbonyl chloride, 3,6-dihydro-; 4-Methyl-δ³-tetrahydro-1,2-oxazine-2-carbonyl chloride; 4-Methyl-3,6-dihydro-2H-1,2-oxazine-2-carboxylic acid chloride; 117593-03-0; 4-Methyl-4,5-dihydro-2H-1,2-oxazine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2H-1,2-Oxazine-2-Carbonyl Chloride, 3,6-Dihydro-4-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.