Description

3H-2,3-Benzoxazine-3-Carbonyl Chloride, 1,4,5,8-Tetrahydro- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique fused benzoxazine-carbonyl chloride structure, which enables the efficient introduction of complex, nitrogen-containing heterocyclic motifs into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, resins, or coatings with specific thermal or mechanical properties.
• Ligand and Catalyst Development: Employed to create sophisticated nitrogen-containing ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function or biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	3H-2,3-Benzoxazine-3-Carbonyl Chloride, 1,4,5,8-Tetrahydro- (9Ci)
CAS No.	117592-95-7
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	1,4,5,8-Tetrahydro-3H-2,3-benzoxazine-3-carbonyl chloride; Tetrahydrobenzoxazinecarbonyl chloride; 3H-2,3-Benzoxazine-3-carbonyl chloride, 1,4,5,8-tetrahydro-; 1,2,3,4-Tetrahydro-2,3-benzoxazine-3-carbonyl chloride; 3-Carboxy-1,4,5,8-tetrahydro-2,3-benzoxazine chloride; 3-Chlorocarbonyl-1,4,5,8-tetrahydro-2,3-benzoxazine
EINECS	Contact for details

Quality Control

Our 3H-2,3-Benzoxazine-3-Carbonyl Chloride, 1,4,5,8-Tetrahydro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure consistent high quality and reliable performance in sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.