Description

Pentanoyl Chloride, 2-Hydroxy-3-Methyl- is a specialized organic acid chloride derivative, distinguished by the presence of both a reactive acyl chloride group and a hydroxyl substituent on the carbon chain. This bifunctional nature makes it a valuable high-purity building block for the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and agrochemical sectors for constructing novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring chiral or branched-chain carboxylic acid derivatives.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce hydroxyl and ester groups into polymer backbones, altering material properties.
• Liquid Crystal & OLED Material Research: Building block for synthesizing advanced organic molecules used in electronic displays and optoelectronic devices.
• Peptide & Prodrug Chemistry: Employed in the acylation of amino groups or the preparation of ester-based prodrugs to improve drug delivery and bioavailability.
• Flavor & Fragrance Industry: Intermediate for producing esters with complex, fruity, or floral notes for high-value aroma chemicals.
• Chemical Research & Development: Versatile reagent for academic and industrial research exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	Pentanoyl Chloride, 2-Hydroxy-3-Methyl-
CAS No.	117486-00-7
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	2-Hydroxy-3-methylpentanoyl chloride; 3-Methyl-2-hydroxypentanoyl chloride; 2-Hydroxy-3-methylvaleryl chloride; α-Hydroxy-β-methylvaleryl chloride; (2R/S)-2-Hydroxy-3-methylpentanoyl chloride (racemic mixture); 3-Methyl-2-oxopentanoic acid chloride (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of Pentanoyl Chloride, 2-Hydroxy-3-Methyl- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets your specific research or production requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.