Description

Stavudine Triphosphate Tea Salt CAS NO 117404-75-8 is a chemically modified nucleotide analog, specifically the triphosphate tea salt derivative of the antiretroviral drug Stavudine. This compound is of critical importance as a high-purity biochemical reagent and a key intermediate in advanced pharmaceutical research and development. It is primarily required by research institutions, pharmaceutical companies, and diagnostic manufacturers engaged in antiviral drug discovery, nucleotide metabolism studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation antiviral prodrugs and nucleotide-based therapeutics.
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies, particularly those involving reverse transcriptase and other DNA/RNA polymerases.
• Antiviral Mechanism Studies: Essential for in-vitro research investigating the mechanism of action, resistance profiles, and metabolic pathways of stavudine and related nucleoside analogs.
• Diagnostic Development: Employed in the development and calibration of diagnostic assays for monitoring antiviral therapy and viral load.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical manufacturing.
• Pre-clinical & Clinical Trials: Utilized in the formulation and testing of novel drug candidates during pre-clinical and clinical development phases.

Basic Information

Item	Detail
Product Name	Stavudine Triphosphate Tea Salt
CAS No.	117404-75-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	d4T Triphosphate Tea Salt; 2',3'-Didehydro-3'-deoxythymidine Triphosphate Tea Salt; Stavudine-5'-triphosphate Tea Salt; d4TTP Tea Salt; 1-((2R,4S,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione Triphosphate Tea Salt
EINECS	Contact for details

Quality Control

Our Stavudine Triphosphate Tea Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.