Description

5-Methyl-Uridine-5'-Monophosphate, Disodium Salt is a modified nucleotide monophosphate salt, a key building block in nucleic acid chemistry and biochemistry. This compound is essential for research and development in areas requiring site-specific RNA modification and metabolic pathway studies. It is primarily utilized by biotechnology firms, pharmaceutical research organizations, and academic institutions focused on oligonucleotide synthesis, enzymology, and molecular biology.

Application

• Oligonucleotide Synthesis: Used as a modified phosphoramidite precursor for the solid-phase synthesis of labeled or functionally altered RNA strands.
• Enzymatic Studies: Serves as a substrate or inhibitor for enzymes like kinases, phosphatases, and polymerases to study catalytic mechanisms and kinetics.
• Metabolic Research: Investigated in nucleotide salvage pathways and the biosynthesis of modified nucleosides and nucleotides.
• Pharmaceutical R&D: A potential intermediate in the development of nucleoside-based antiviral or anticancer prodrugs.
• Biochemical Reagent: Employed in the preparation of customized nucleotide pools for in vitro transcription and translation systems.
• Diagnostic Probe Development: Can be incorporated into nucleic acid probes to enhance stability or alter hybridization properties.

Basic Information

Product Name	5-Methyl-Uridine-5'-Monophosphate, Disodium Salt
CAS No.	117309-80-5
Molecular Formula	C10H13N2Na2O9P
Molecular Weight	388.16 g/mol
Synonyms	5-Methyluridine 5'-(disodium phosphate); 5-Methyl-UMP disodium salt; Disodium 5-methyluridine 5'-monophosphate; 5-Methyluridylic acid disodium salt; m5UMP disodium salt; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxy)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4-dione disodium salt
EINECS	Contact for details

Quality Control

Our 5-Methyl-Uridine-5'-Monophosphate, Disodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets rigorous research-grade specifications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.