Description

Benzeneacetyl Chloride, 4-Methoxy-α-Oxo- (9Ci) is a specialized aromatic acid chloride derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in its dual reactive sites—the acid chloride and the α-keto group—which enable precise and efficient construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to introduce key functional motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing benzoyl or phenacyl moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugation: Employed for the acylation of amines to create amide bonds, useful in peptide analog synthesis and bioconjugation chemistry.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for creating novel polymers and organic electronic materials with specific optical or electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	Benzeneacetyl Chloride, 4-Methoxy-α-Oxo- (9Ci)
CAS No.	117177-66-9
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	4-Methoxyphenacyl chloride; 2-Chloro-1-(4-methoxyphenyl)ethanone; p-Methoxyphenacyl chloride; 4-Methoxy-α-oxobenzeneacetyl chloride; 4-Methoxybenzoyl methyl chloride; 1-(4-Methoxyphenyl)-2-chloroethanone; 4-Methoxy-ω-chloroacetophenone; 4-Methoxyphenyl chloromethyl ketone
EINECS	Contact for details

Quality Control

Our Benzeneacetyl Chloride, 4-Methoxy-α-Oxo- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.