Description

6-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyridine-2-Carboxamide is a high-purity nucleoside analog derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate in the synthesis of novel therapeutic agents, particularly those targeting viral infections and specific enzymatic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of nucleoside-based drugs. The precise stereochemistry and functional groups of this molecule make it a valuable scaffold for creating potent and selective bioactive compounds.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and mechanism of action.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation of related pharmaceutical products.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies in organic synthesis, carbohydrate chemistry, and heterocyclic compound behavior.

Basic Information

Product Name	6-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyridine-2-Carboxamide
CAS No.	117134-30-2
Molecular Formula	C12H16N2O6
Molecular Weight	284.27 g/mol
Synonyms	2-Pyridinecarboxamide, 6-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-; 6-(β-D-Ribofuranosyl)picolinamide; 6-(β-D-Ribofuranosyl)pyridine-2-carboxamide; 2-Carbamoyl-6-(β-D-ribofuranosyl)pyridine; Picolinamide ribonucleoside derivative; (2S,3S,4R,5R)-2-(6-Carbamoylpyridin-2-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
EINECS	Contact for details

Quality Control

Our 6-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyridine-2-Carboxamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.