Description

1H-Indole-1-Carbonyl Chloride, 2,3-Dihydro-3,3-Dimethyl- (9Ci) is a specialized indole derivative and a reactive acyl chloride intermediate. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides with specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Bioconjugation Chemistry: Employed for labeling and modifying biomolecules due to its reactive carbonyl chloride group.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	1H-Indole-1-Carbonyl Chloride, 2,3-Dihydro-3,3-Dimethyl- (9Ci)
CAS No.	117086-95-0
Molecular Formula	C12H12ClNO
Molecular Weight	221.68 g/mol
Synonyms	2,3-Dihydro-3,3-dimethyl-1H-indole-1-carbonyl chloride; 3,3-Dimethylindoline-1-carbonyl chloride; 1-Carboxy-2,3-dihydro-3,3-dimethylindole chloride; 1H-Indole-1-carbonyl chloride, 2,3-dihydro-3,3-dimethyl-; 3,3-Dimethyl-2,3-dihydro-1H-indole-1-carbonyl chloride; N-Carboxy-3,3-dimethylindoline chloride; Indoline-1-carbonyl chloride, 3,3-dimethyl-
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carbonyl Chloride, 2,3-Dihydro-3,3-Dimethyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.