Description

1,2-Dipalmitoylphosphatidylfluorouridine is a synthetic, fluorinated phospholipid-nucleoside conjugate designed for advanced research and development. This compound is engineered to enhance the stability and cellular delivery of nucleoside analogs, making it a critical tool for targeted therapeutic strategies. It is primarily utilized by pharmaceutical researchers and biotech companies working on novel drug delivery systems, particularly in oncology and antiviral applications.

Application

• Liposomal Drug Delivery: A key component in the formulation of advanced liposomes for the targeted delivery of chemotherapeutic and antiviral agents.
• Prodrug Development: Serves as a sophisticated prodrug linker to improve the pharmacokinetics and bioavailability of nucleoside-based pharmaceuticals.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies involving phospholipases and nucleotide metabolism.
• Cell Membrane Studies: Acts as a fluorescent or modified phospholipid probe for investigating membrane dynamics, fusion, and cellular uptake mechanisms.
• Nanomedicine: Incorporated into nanostructured lipid carriers (NLCs) and other nanoparticles to create smart, responsive drug delivery platforms.

Basic Information

Product Name	1,2-Dipalmitoylphosphatidylfluorouridine
CAS No.	116662-09-0
Molecular Formula	C46H81FN2O14P
Molecular Weight	936.11 g/mol
Synonyms	DPPF-Uridine; 1,2-Dihexadecanoyl-sn-glycero-3-phospho-5-fluorouridine; Fluorouridine dipalmitoylphosphatidyl ester; 5-Fluorouridine 1,2-dipalmitoylphosphatidyl derivative; Phosphatidylfluorouridine; DPPF-UR; 5-FUDPP; 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-5'-fluorouridine)
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoylphosphatidylfluorouridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider sealing under vacuum or an inert gas such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.