Description

9-[(2R,4S,5S)-4-Azido-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is a high-purity nucleoside analog, specifically a modified adenosine derivative, designed for advanced pharmaceutical research and development. This compound is a critical building block for the synthesis of novel antiviral and anticancer agents, offering researchers a precise tool for probing biological mechanisms. It is primarily utilized by pharmaceutical R&D laboratories and biotech companies engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside-based antiviral drugs targeting viral polymerases.
• Anticancer Agent Development: Used in research for creating prodrugs and targeted therapies that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe: Serves as a tool compound in enzymatic studies and for investigating nucleotide metabolism pathways.
• Antiviral Research: Integral to the development of novel treatments for a range of viral infections.
• Labeled Compound Synthesis: The azido group provides a handle for "click chemistry" applications, enabling the creation of fluorescent or affinity-labeled probes for diagnostic and imaging purposes.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	9-[(2R,4S,5S)-4-Azido-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One
CAS No.	116597-13-8
Molecular Formula	C11H13N7O3
Molecular Weight	291.27 g/mol
Synonyms	4'-Azido-2'-deoxyadenosine; 4'-Azido-2'-deoxyadenosine (4'-N3-2'-dA); 2'-Deoxy-4'-azidoadenosine; 9-(4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol; 4'-Azidoadenosine derivative; Azidonucleoside; 4'-N3-dA
EINECS	Contact for details

Quality Control

Our 9-[(2R,4S,5S)-4-Azido-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant GMP guidelines for the production of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. For long-term storage, desiccate to protect from moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.