Description

7-Iodo-8-Hydroxy-3-Methyl-1-(4-Azidophenyl)-2,3,4,5-Tetrahydro-1H-3-Benzazepine is a sophisticated, multifunctional benzazepine derivative designed for advanced research and development. This compound is valued for its unique molecular architecture, which incorporates an azido group and an iodine substituent, making it a versatile intermediate for click chemistry, photolabeling, and medicinal chemistry programs. It is primarily sought by pharmaceutical researchers, agrochemical developers, and academic institutions engaged in the synthesis of novel bioactive molecules and molecular probes.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel central nervous system (CNS) targeting agents and receptor ligands.
• Click Chemistry Reagent: The azido functional group enables efficient, selective conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and material science applications.
• Photoaffinity Labeling Probe: Used in proteomics and drug discovery to identify and study drug-target interactions and binding sites.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Agrochemical Development: Investigated as a precursor for novel crop protection agents with specific biological activity.
• Chemical Biology Tool: Employed in the development of molecular probes for imaging, diagnostics, and understanding biological pathways.

Basic Information

Product Name	7-Iodo-8-Hydroxy-3-Methyl-1-(4-Azidophenyl)-2,3,4,5-Tetrahydro-1H-3-Benzazepine
CAS No.	116234-50-5
Molecular Formula	C17H17IN4O
Molecular Weight	420.25 g/mol
Synonyms	1-(4-Azidophenyl)-7-iodo-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 7-Iodo-8-hydroxy-3-methyl-1-(4-azidophenyl)-1,2,4,5-tetrahydro-3H-3-benzazepine; 1-(4-Azidophenyl)-7-iodo-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine; Benzazepine derivative, 7-iodo-8-hydroxy-3-methyl-1-(4-azidophenyl)-2,3,4,5-tetrahydro-; CAS 116234-50-5
EINECS	Contact for details

Quality Control

Our production of 7-Iodo-8-Hydroxy-3-Methyl-1-(4-Azidophenyl)-2,3,4,5-Tetrahydro-1H-3-Benzazepine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.