Description

4-Amino-8-(Ribofuranosylamino)Pyrimido(5,4-D)Pyrimidine-5'-Phosphate is a specialized nucleotide analog with significant biochemical relevance. This compound is valued for its role as a key intermediate and research tool in the development of novel therapeutic agents and biochemical probes. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleotide metabolism, enzyme inhibition studies, and antiviral or anticancer drug discovery.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine and pyrimidine metabolism.
• Probe Development: Serves as a precursor for fluorescent or radiolabeled probes to study cellular processes and target engagement.
• Enzyme Kinetics: Employed in assays to determine the kinetics and mechanism of action of kinases, phosphorylases, and other nucleotide-processing enzymes.
• Academic Research: Fundamental tool for investigating nucleotide analog biochemistry and structure-activity relationships (SAR).
• Preclinical Development: Used in early-stage drug discovery for in vitro and in vivo efficacy and toxicity profiling of new chemical entities.

Basic Information

Product Name	4-Amino-8-(Ribofuranosylamino)Pyrimido(5,4-D)Pyrimidine-5'-Phosphate
CAS No.	116168-71-9
Molecular Formula	C11H15N6O8P
Molecular Weight	390.25 g/mol
Synonyms	8-Amino-4-(ribofuranosylamino)pyrimido[5,4-d]pyrimidine 5'-phosphate; 4-Amino-8-(β-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine 5'-phosphate; 4-Amino-8-(ribofuranosylamino)pyrimido[5,4-d]pyrimidine 5'-monophosphate; Nucleotide analog 116168-71-9; Pyrimido[5,4-d]pyrimidine ribonucleotide derivative; 4-Amino-8-(ribosylamino)pyrimido[5,4-d]pyrimidine phosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for our research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.