Description

4-Bromo-2-(Methoxyimino)-3-Oxobutyrylchloride is a specialized, high-purity organic intermediate characterized by its reactive acid chloride and brominated oxime functional groups. This compound matters as a critical building block for synthesizing complex molecules, particularly in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic compounds and functionalized structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antibiotic candidates and other complex drug molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in research and development for creating custom-designed molecules with specific biological activities.
• Heterocyclic Chemistry: Serves as a versatile reagent for constructing pyrazole, isoxazole, and other nitrogen/oxygen-containing heterocycles.
• Cross-Coupling Reactions: The bromine moiety makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and enzyme inhibitors.

Basic Information

Product Name	4-Bromo-2-(Methoxyimino)-3-Oxobutyrylchloride
CAS No.	115922-43-5
Molecular Formula	C6H7BrClNO3
Molecular Weight	256.48 g/mol
Synonyms	4-Bromo-2-(methoxyimino)-3-oxobutanoyl chloride; 4-Bromo-3-oxo-2-(O-methyloximino)butyryl chloride; 2-(Methoxyimino)-4-bromo-3-oxobutyryl chloride; α-Bromoacetoacetic acid O-methyloxime chloride; Bromoacetoacetic acid methyloxime chloride; Butanoyl chloride, 4-bromo-2-(methoxyimino)-3-oxo-; (E)-4-Bromo-2-(methoxyimino)-3-oxobutanoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Methoxyimino)-3-Oxobutyrylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.