Description

Bicyclo[1.1.1]pentane-1,3-dicarbonyl dichloride (9Ci) is a highly functionalized, strained bicyclic building block of significant interest in modern organic synthesis. Its unique three-dimensional [1.1.1]propellane-derived structure and reactive acid chloride groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, ligand design, and polymer chemistry.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel, three-dimensional bioactive molecules and fragments in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Advanced Materials: Precursor for monomers and cross-linkers in the synthesis of high-performance polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Serves as a rigid scaffold for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying protein-ligand interactions and biological pathways.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical space in organic chemistry.

Basic Information

Item	Details
Product Name	Bicyclo[1.1.1]pentane-1,3-dicarbonyl dichloride (9Ci)
CAS No.	115913-31-0
Molecular Formula	C7H6Cl2O2
Molecular Weight	193.03 g/mol
Synonyms	1,3-Bicyclo[1.1.1]pentanedicarbonyl dichloride; [1.1.1]Propellane-1,3-dicarbonyl dichloride; BCP-diacid chloride; 1,3-Dicarbonylchloridobicyclo[1.1.1]pentane; Pentane-1,3-dicarbonyl dichloride, bicyclo[1.1.1]- (9CI); Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid dichloride
EINECS	Contact for details

Quality Control

Our Bicyclo[1.1.1]pentane-1,3-dicarbonyl dichloride is produced under strict quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive R&D and scale-up processes. All materials are characterized by modern analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.