Description

Tfa-Ap-Du CAS NO 115899-40-6 is a specialized organic compound, specifically a protected amino acid derivative, widely utilized in advanced chemical synthesis. This high-purity intermediate is critical for ensuring precise molecular assembly and consistent batch-to-batch performance in sensitive applications. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of peptides, active pharmaceutical ingredients (APIs), and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of novel peptide-based therapeutics and drug candidates.
• Peptide Synthesis: Used as a protected amino acid derivative to introduce specific functional groups during the sequential assembly of custom peptides.
• Bioconjugation: Serves as a reagent for the controlled modification of proteins, antibodies, or other biomolecules in drug delivery and diagnostic applications.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic pathways and developing novel chemical entities.
• API Manufacturing: An essential intermediate in the multi-step synthesis of complex active pharmaceutical ingredients requiring high stereochemical purity.

Basic Information

Product Name	Tfa-Ap-Du
CAS No.	115899-40-6
Molecular Formula	C14H15F3N2O5
Molecular Weight	348.28 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[(2,2,2-trifluoroacetyl)amino]-L-alanine; Fmoc-Dap(Tfa)-OH; Fmoc-L-2,3-diaminopropionic acid (Tfa); Nα-Fmoc-Nβ-Tfa-L-2,3-diaminopropanoic acid; Fmoc-3-amino-L-alanine(Tfa); Nα-Fmoc-Nβ-(trifluoroacetyl)-L-2,3-diaminopropionic acid; Fmoc-Dap(Tfa)-OH
EINECS	Contact for details

Quality Control

Our Tfa-Ap-Du is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical research and production. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.