Description

Tfa-Ap-Dc CAS NO 115899-38-2 is a specialized chemical intermediate, primarily recognized as a protected amino acid derivative. This compound is critical for advanced organic synthesis, particularly in peptide chemistry, where it serves as a key building block for constructing complex molecular architectures. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on developing novel therapeutic agents and bioactive compounds.

Application

• Peptide Synthesis: A crucial protected intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the R&D of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and metabolic disorders.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Proteomics & Biochemistry: Employed in the study of protein structure and function, and in the synthesis of enzyme inhibitors.
• Fine Chemical Production: A valuable intermediate for manufacturing custom-designed molecules with specific chiral centers and functional groups.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	Tfa-Ap-Dc
CAS No.	115899-38-2
Molecular Formula	C15H16F3NO5
Molecular Weight	347.29 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[(2,2,2-trifluoroacetyl)amino]-L-alanine; Fmoc-3-(Tfa-amino)-L-alanine; Fmoc-Dap(Tfa)-OH; 3-[(2,2,2-Trifluoroacetyl)amino]-L-alanine N-[(9H-fluoren-9-ylmethoxy)carbonyl]; Fmoc-L-2,3-diaminopropionic acid(Tfa); Nα-Fmoc-Nβ-Tfa-L-2,3-diaminopropionic acid
EINECS	Contact for details

Quality Control

Our Tfa-Ap-Dc is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications to ensure it meets the stringent requirements for pharmaceutical research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.