Description

3-Indolizinecarbonylchloride,1-Methyl-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key acyl chloride intermediate, enabling the efficient introduction of the 1-methylindolizine moiety into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the indolizine scaffold can contribute to unique biological activity.
• Material Science: Employed in the creation of advanced organic materials, such as organic semiconductors or light-emitting compounds, due to its conjugated structure.
• Chemical Biology: Acts as a derivatization agent or a probe-building block for studying biological systems and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.

Basic Information

Item	Detail
Product Name	3-Indolizinecarbonylchloride,1-Methyl-(9Ci)
CAS No.	115813-14-4
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	1-Methylindolizine-3-carbonyl chloride; 1-Methyl-3-indolizinecarbonyl chloride; 1-Methyl-1H-pyrrolo[1,2-a]pyridine-3-carbonyl chloride; 1-Methylindolizine-3-carboxylic acid chloride; 3-Carboxy-1-methylindolizine chloride; (1-Methylindolizin-3-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Indolizinecarbonylchloride,1-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.