Description

1H-Tetrazole-5-Carbonyl Chloride, 1-Methoxy- (9Ci) is a specialized heterocyclic building block and key acyl chloride intermediate. This compound matters for its high reactivity, enabling efficient derivatization and the introduction of the tetrazole moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing tetrazole rings, which are important bioisosteres for carboxylic acids.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the tetrazole scaffold imparts specific biological activity.
• Peptide Chemistry & Bioconjugation: Serves as a reactive handle for coupling reactions, facilitating the modification of peptides, proteins, and other biomolecules.
• Material Science Research: Employed in the development of advanced polymers, ligands for catalysis, and functional materials requiring specific heterocyclic components.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying enzymatic function and biological pathways.
• Scale-up & Process Chemistry: Suitable for optimization in pilot plant and commercial-scale manufacturing of high-value specialty chemicals.

Basic Information

Product Name	1H-Tetrazole-5-Carbonyl Chloride, 1-Methoxy- (9Ci)
CAS No.	115751-80-9
Molecular Formula	C3H3ClN4O2
Molecular Weight	162.53 g/mol
Synonyms	1-Methoxy-1H-tetrazole-5-carbonyl chloride; 1-Methoxy-1H-tetrazole-5-carboxylic acid chloride; 1-Methoxy-1H-tetrazole-5-carbonyl chloride (9CI); 1-Methoxy-1H-tetrazole-5-carboxylic chloride; 1-Methoxy-1H-tetrazole-5-carbonylchloride; 1-Methoxy-1H-tetrazole-5-carboxychloride; 1-Methoxy-1H-tetrazol-5-yl carbonyl chloride; 1-Methoxy-1H-tetrazol-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Tetrazole-5-Carbonyl Chloride, 1-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.