Description

6'-Fluoroaristeromycin is a fluorinated nucleoside analog and a key intermediate in medicinal chemistry research. This compound matters for its role in the development of novel antiviral and anticancer agents, where the fluorine substitution can significantly alter biological activity and metabolic stability. Pharmaceutical researchers and fine chemical manufacturers need it for synthesizing advanced nucleotide-based therapeutics and for probing enzyme mechanisms in biochemical studies.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly targeting S-adenosylhomocysteine hydrolase (SAHase).
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for its potential activity against a range of viral pathogens due to its mechanism as an adenosine analog.
• Labeled Compound Synthesis: Can be used as a precursor for the preparation of radiolabeled or isotopically labeled tracers for metabolic studies.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in nucleoside chemistry and virology.

Basic Information

Product Name	6'-Fluoroaristeromycin
CAS No.	115509-32-5
Molecular Formula	C12H16FN5O3
Molecular Weight	297.29 g/mol
Synonyms	6'-Fluoroaristeromycin; 6'-Deoxy-6'-fluoroadenosine; 6'-Fluoro-9-(2,3-dideoxy-β-D-erythro-pent-2-enofuranosyl)adenine; 6'-Fluoro-9-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine; 6'-F-Ado; 6'-Fluoro-2',3'-didehydro-2',3'-dideoxyadenosine; 6'-Fluoro-D4A; Fluorinated aristeromycin analog
EINECS	Contact for details

Quality Control

Our 6'-Fluoroaristeromycin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.