Description

2'-Methyl-2'-Deoxycytidine is a chemically modified nucleoside analog, a key building block in oligonucleotide synthesis and pharmaceutical research. This compound is valued for its role in creating modified nucleic acid sequences with enhanced stability and specific biological properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic probes, and advanced biochemical studies.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
• Antiviral & Anticancer Research: Serves as a core scaffold in the development of nucleoside-based prodrugs and therapeutic agents.
• Biochemical Probes: Used to create labeled or modified nucleotides for studying enzyme mechanisms, such as methyltransferases.
• Medicinal Chemistry: An intermediate in the synthesis of more complex pharmaceutical candidates targeting genetic diseases.
• Diagnostic Development: Incorporated into probes for PCR, sequencing, and other molecular diagnostic techniques to enhance specificity.

Basic Information

Product Name	2'-Methyl-2'-Deoxycytidine
CAS No.	115494-53-6
Molecular Formula	C10H15N3O4
Molecular Weight	241.25 g/mol
Synonyms	2'-C-Methyl-2'-deoxycytidine; 1-(2-C-Methyl-β-D-ribofuranosyl)cytosine; 2'-Methylcytidine; 2'-C-Methylcytidine; 2'-Me-dC; 2'-Methyl-deoxycytidine
EINECS	Contact for details

Quality Control

Our 2'-Methyl-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.