Description

4-Methoxy-7--D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the preparation of novel antiviral and anticancer agents, particularly those targeting RNA-based mechanisms. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleosides and oligonucleotides for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Oligonucleotide Synthesis: Employed in the preparation of modified antisense oligonucleotides and siRNA constructs for genetic research and therapy.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies involving nucleoside-processing enzymes.
• Process Development: Serves as a reference standard and starting material for scaling up the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Methoxy-7--D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	115479-42-0
Molecular Formula	C₁₂H₁₆N₄O₅
Molecular Weight	296.28 g/mol
Synonyms	7-Deaza-2-amino-7-(β-D-ribofuranosyl)-4-methoxypyrrolo[2,3-d]pyrimidine; 4-Methoxy-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 2-Amino-4-methoxy-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-methoxy-7-β-D-ribofuranosyl-; Modified Nucleoside Intermediate; Pyrrolopyrimidine Nucleoside
EINECS	Contact for details

Quality Control

Our 4-Methoxy-7--D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.