Description

1,3,4-Tri-o-Acetyl-2-Azido-2-Deoxy-α-L-Fucopyranose is a key acetylated and azido-functionalized monosaccharide derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a protected, reactive handle for the stereoselective construction of complex glycoconjugates and bioactive molecules. This high-purity intermediate is essential for research and development in the pharmaceutical and biotechnology sectors, particularly for the synthesis of novel therapeutics, vaccines, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogs, antiviral agents, and other small-molecule therapeutics.
• Glycoconjugate Synthesis: Used as a key building block for constructing complex oligosaccharides, glycopeptides, and glycolipids via "click chemistry" and other coupling reactions.
• Carbohydrate Chemistry Research: Serves as a standard reagent and starting material in academic and industrial research for studying glycosylation mechanisms and developing new synthetic methodologies.
• Bioconjugation & Probe Development: The azido group enables efficient, bioorthogonal conjugation (e.g., CuAAC, SPAAC) for labeling biomolecules, creating targeted drug delivery systems, and developing diagnostic imaging agents.
• Vaccine Adjuvant Development: Investigated for use in the synthesis of synthetic carbohydrate antigens and adjuvant components to modulate immune responses.
• Material Science: Potential monomer for creating specialized polymers and hydrogels with bioactive or tunable properties.

Basic Information

Product Name	1,3,4-Tri-o-Acetyl-2-Azido-2-Deoxy-α-L-Fucopyranose
CAS No.	115435-17-1
Molecular Formula	C₁₂H₁₇N₃O₈
Molecular Weight	331.28 g/mol
Synonyms	2-Azido-2-deoxy-1,3,4-tri-O-acetyl-α-L-fucopyranose; 1,3,4-Tri-O-acetyl-2-azido-2-deoxy-α-L-fucopyranose; α-L-Fucopyranose, 2-azido-2-deoxy-, 1,3,4-triacetate; 2-Azido-1,3,4-tri-O-acetyl-2-deoxy-α-L-fucopyranose; Acetylated L-Fucose Azide Derivative; L-Fucose Azide Triacetate
EINECS	Contact for details

Quality Control

Our 1,3,4-Tri-o-Acetyl-2-Azido-2-Deoxy-α-L-Fucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research and cGMP-grade requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.