Description

1H-Imidazole-4-Carbonyl Chloride, 5-Cyano- (9Ci) is a high-purity, reactive chemical intermediate featuring a cyano-substituted imidazole core activated by an acid chloride group. This compound matters for its critical role in the synthesis of complex heterocyclic molecules, enabling the construction of advanced pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is relevant.
• Agrochemical Research: Used in developing novel fungicides, herbicides, or insecticides that incorporate heterocyclic structures for enhanced bioactivity.
• Material Science: Serves as a precursor for functional polymers, ligands for metal-organic frameworks (MOFs), or advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) or affinity labels to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	1H-Imidazole-4-Carbonyl Chloride, 5-Cyano- (9Ci)
CAS No.	115363-80-9
Molecular Formula	C5H2ClN3O
Molecular Weight	155.54 g/mol
Synonyms	5-Cyano-1H-imidazole-4-carbonyl chloride; 5-Cyanoimidazole-4-carbonyl chloride; 4-Cyanoimidazole-5-carbonyl chloride; 1H-Imidazole-4-carbonyl chloride, 5-cyano-; 5-Cyano-1H-imidazole-4-carboxylic acid chloride; 5-CN-Im-4-COCl
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carbonyl Chloride, 5-Cyano- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.