Description

2H-Pyran-2-Carbonyl Chloride, Tetrahydro-2-Methyl- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity, enabling efficient acylation and ring-opening reactions to construct complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its tetrahydro-2-methylpyran scaffold contributes to bioactive molecule design.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.
• Academic & Contract Research: A valuable reagent for methodological studies and exploratory research in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2H-Pyran-2-Carbonyl Chloride, Tetrahydro-2-Methyl- (9Ci)
CAS No.	115261-81-9
Molecular Formula	C7H9ClO2
Molecular Weight	160.60 g/mol
Synonyms	2-Methyltetrahydro-2H-pyran-2-carbonyl chloride; Tetrahydro-2-methyl-2H-pyran-2-carbonyl chloride; 2-(Chlorocarbonyl)-2-methyltetrahydropyran; 2-Methyltetrahydropyran-2-carbonyl chloride; 2-Methyl-5,6-dihydro-2H-pyran-2-carbonyl chloride (related tautomer); 2H-Pyran-2-carbonyl chloride, tetrahydro-2-methyl-; 115261-81-9 (CAS); 2-Methyl-2-tetrahydropyranecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-2-Carbonyl Chloride, Tetrahydro-2-Methyl- (9Ci) is manufactured under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.