Description

14-Methylcholesterol is a specific methylated derivative of cholesterol, a key sterol in biological systems. This compound is of significant interest in research and development for its role in studying sterol metabolism, membrane biophysics, and as a potential synthetic intermediate. It serves as a valuable analytical standard and building block for scientists and manufacturers in the pharmaceutical, life science, and specialty chemical sectors.

Application

• Biochemical Research: Used as a reference standard in analytical methods (GC, HPLC) for the study of sterol biosynthesis and metabolic pathways.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor or intermediate in the development of novel therapeutic agents and steroid-based drugs.
• Membrane Studies: Employed in biophysical research to investigate the effects of modified sterols on membrane fluidity, structure, and function.
• Academic & Industrial R&D: A critical reagent for exploring new chemical entities and conducting structure-activity relationship (SAR) studies in medicinal chemistry.
• Analytical Chemistry: Functions as a high-purity internal standard or calibrant for the accurate quantification of sterols in complex matrices.
• Specialty Chemical Synthesis: Utilized as a building block for the synthesis of more complex steroidal compounds and fine chemicals.

Basic Information

Product Name	14-Methylcholesterol
CAS No.	115090-73-8
Molecular Formula	C₂₈H₄₈O
Molecular Weight	400.68 g/mol
Synonyms	14α-Methylcholest-5-en-3β-ol; 14-Methylcholest-5-en-3β-ol; 14-Methyl-δ⁵-cholesten-3β-ol; 14-Methyl cholesterol; (3β)-14-Methylcholest-5-en-3-ol; 14-Methyl-cholest-5-ene-3β-ol; 14α-Methyl cholesterol
EINECS	Contact for details

Quality Control

Our 14-Methylcholesterol is produced and tested under a strict quality management system. We provide material suitable for research and development applications, with typical purity levels exceeding 95% (by HPLC). Each batch is accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and related substances are available upon request to ensure traceability and meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/Certificate of Analysis. For long-term storage, consider under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.