Description

5-Chloro-1H-[1,2,3]Triazole-4-Carbonyl Azide is a versatile and highly reactive heterocyclic building block. This compound is valued for its azide functional group, which enables efficient click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel triazole-containing molecules, which are key scaffolds in drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing active pharmaceutical ingredients (APIs) containing the 1,2,3-triazole core, a privileged structure in medicinal chemistry.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage the triazole moiety for biological activity.
• Click Chemistry Reagent: Serves as a key reactant in CuAAC reactions for the rapid and reliable assembly of complex molecular architectures in drug discovery and materials science.
• Polymer Modification: Employed to functionalize polymers and surfaces via azide-alkyne coupling, creating advanced materials with tailored properties.
• Bioconjugation: Facilitates the labeling and linking of biomolecules (e.g., proteins, peptides) for diagnostic and therapeutic applications.
• Chemical Biology Probes: Used to create activity-based probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Chloro-1H-[1,2,3]Triazole-4-Carbonyl Azide
CAS No.	115057-46-0
Molecular Formula	C3HClN4O
Molecular Weight	144.52 g/mol
Synonyms	5-Chloro-1H-1,2,3-triazole-4-carbonyl azide; 5-Chloro-1H-[1,2,3]triazole-4-carboxylic acid azide; 4-Azidocarbonyl-5-chloro-1H-1,2,3-triazole; 5-Chloro-1H-1,2,3-triazole-4-carbonyl azide; 5-Chloro-1,2,3-triazole-4-carbonyl azide; 5-Chloro-1H-triazole-4-carbonyl azide; 115057-46-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-1H-[1,2,3]Triazole-4-Carbonyl Azide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of the reactive azide group, this material should be handled with appropriate care and stored separately from incompatible materials. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.