Description

2-Methyl-2-(4-(Trifluoromethoxy)Phenyl)Propan-1-Ol is a specialized organic compound featuring a trifluoromethoxy-substituted aromatic ring, a structure that imparts unique physicochemical properties valuable for advanced chemical synthesis. This compound serves as a critical building block (synthon) in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine-containing groups is a key strategy for modulating bioactivity and stability. It is primarily sought by R&D chemists and process development scientists in fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Intermediate: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorine-containing aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, esterifications, and etherifications as a robust, sterically hindered alcohol component.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	2-Methyl-2-(4-(Trifluoromethoxy)Phenyl)Propan-1-Ol
CAS No.	115012-42-5
Molecular Formula	C11H13F3O2
Molecular Weight	234.22 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-2-methylpropan-1-ol; α,α-Dimethyl-4-(trifluoromethoxy)benzenemethanol; 2-Methyl-2-[4-(trifluoromethoxy)phenyl]-1-propanol; 4-(Trifluoromethoxy)-α,α-dimethylbenzenemethanol; 2-Methyl-2-(p-trifluoromethoxyphenyl)propan-1-ol; (4-(Trifluoromethoxy)phenyl)dimethylmethanol
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(4-(Trifluoromethoxy)Phenyl)Propan-1-Ol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and scale-up with custom purity grades and can provide material suitable for cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.