Description

Diethyl Fluoro(Phenylsulfonyl)Methylphosphonate is a specialized organophosphorus compound that serves as a valuable building block in advanced organic synthesis. This chemical matters for its unique reactivity, enabling the efficient introduction of fluorinated and sulfonylated methylphosphonate groups into target molecules. Pharmaceutical researchers and agrochemical developers need it for creating novel active ingredients, particularly in the design of enzyme inhibitors and bioactive probes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially protease and kinase inhibitors.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides with modified activity and environmental profiles.
• Chemical Biology & Medicinal Chemistry: Employed as a versatile building block for synthesizing fluorinated analogs and activity-based probes for target identification.
• Material Science Research: Investigated for the preparation of specialty monomers or additives to impart specific properties to polymers.
• Organocatalysis & Ligand Development: Serves as a precursor for novel phosphonate-based ligands or catalysts in asymmetric synthesis.
• Academic & R&D Laboratories: Utilized in methodological development for new C-P and C-F bond-forming reactions.

Basic Information

Product Name	Diethyl Fluoro(Phenylsulfonyl)Methylphosphonate
CAS No.	114968-97-7
Molecular Formula	C11H16FO5PS
Molecular Weight	310.28 g/mol
Synonyms	Diethyl (Fluoro(phenylsulfonyl)methyl)phosphonate; (Fluoro(phenylsulfonyl)methyl)phosphonic Acid Diethyl Ester; Diethyl (Fluorobenzenesulfonylmethyl)phosphonate; Phosphonic acid, P-[fluoro(phenylsulfonyl)methyl]-, diethyl ester; Diethyl (fluoro(phenylsulfonyl)methyl)phosphonate; Fluoro(phenylsulfonyl)methylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl Fluoro(Phenylsulfonyl)Methylphosphonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of R&D and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual ≤ 1.0%; Total ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.