Description

2-Chloro-2'-Deoxy-3,7-Dideazaadenosine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile building block for the creation of novel therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors, particularly those focused on antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Antiviral Drug Development: Serves as a core scaffold for modifying to target viral polymerases and reverse transcriptases.
• Medicinal Chemistry: A valuable building block for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Labeled Compound Synthesis: Can be used to create isotopically labeled versions for metabolic tracing and pharmacokinetic studies.
• Academic Research: Employed in university and institutional labs for fundamental research in chemical biology and drug design.

Basic Information

Product Name	2-Chloro-2'-Deoxy-3,7-Dideazaadenosine
CAS No.	114915-05-8
Molecular Formula	C₁₁H₁₂ClN₅O₃
Molecular Weight	297.70 g/mol
Synonyms	2-Chloro-2'-deoxy-3,7-dideazaadenosine; 2-Chloro-7-deaza-2'-deoxyadenosine; 2-Chloro-2'-deoxytubercidin; 7-Deaza-2-chloro-2'-deoxyadenosine; 2-Cl-2'-dA; 2-Chloro-2'-deoxy-7-deazaadenosine; 2-Chloro-7-deaza-dA; 2'-Deoxy-2-chloro-3,7-dideazaadenosine
EINECS	Contact for details

Quality Control

Our 2-Chloro-2'-Deoxy-3,7-Dideazaadenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.