Description

2-Bromo-2',3'-Dideoxyadenosine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly nucleoside reverse transcriptase inhibitors. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs). The product is supplied under stringent quality control to ensure consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside-based antiviral drugs.
• Antiviral Research: Used in the development and study of compounds targeting viral polymerases and reverse transcriptases.
• Anticancer Agent Development: Serves as a precursor for potential chemotherapeutic nucleoside analogs.
• Biochemical Research: Employed in studies of nucleic acid chemistry, enzyme inhibition, and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, functionalized nucleoside derivatives.
• Probe and Diagnostic Development: Can be utilized in creating labeled compounds for biological assays and imaging studies.

Basic Information

Product Name	2-Bromo-2',3'-Dideoxyadenosine
CAS No.	114849-57-9
Molecular Formula	C10H11BrN5O2
Molecular Weight	313.13 g/mol
Synonyms	2-Bromo-2',3'-ddA; 9-[(2R,5S)-5-(Bromomethyl)tetrahydrofuran-2-yl]-9H-purin-6-amine; 2-Bromo-ddA; 2-Br-2',3'-dideoxyadenosine; 2-Bromo-2',3'-dideoxy-adenosine; Adenosine, 2-bromo-2',3'-dideoxy-
EINECS	Contact for details

Quality Control

Our 2-Bromo-2',3'-Dideoxyadenosine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical synthesis. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.