Description

3'-Fluoro-2,6-Diaminopurine-2',3'-Dideoxyriboside is a modified nucleoside analog, a key building block in medicinal chemistry and life science research. Its value lies in its role as a versatile intermediate for the synthesis of novel antiviral and anticancer nucleotide analogs. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing nucleoside-based therapeutics targeting viral replication and cellular proliferation.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair mechanisms.
• Antiviral Agent Development: Serves as a core scaffold for creating nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
• Oncology Research: Investigated for incorporation into oligonucleotides or as a standalone agent to study its effects on tumor cell growth.
• Proteomics & Genomics: Employed in the development of specialized probes and tools for studying nucleic acid interactions and functions.
• Chemical Biology: Utilized to create labeled or modified nucleotides for tracking metabolic pathways.

Basic Information

Product Name	3'-Fluoro-2,6-Diaminopurine-2',3'-Dideoxyriboside
CAS No.	114753-53-6
Molecular Formula	C10H12FN7O2
Molecular Weight	281.25 g/mol
Synonyms	2,6-Diaminopurine-2',3'-dideoxy-3'-fluororiboside; 3'-Fluoro-2',3'-dideoxy-2,6-diaminopurine riboside; 9-[(2R,5S)-5-Fluoro-2,5-dihydro-2-furanyl]-2,6-diamino-9H-purine; 3'-F-ddDAPR; 3'-Fluoro-2',3'-dideoxy-2,6-diaminopurine; 2,6-Diamino-9-(3-fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)purine; 3'-F-2',3'-ddDAPR
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-2,6-Diaminopurine-2',3'-Dideoxyriboside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.