Description

Triphosphoric Acid, p-[[(2S,5R)-5-[4-Amino-5-(3-Amino-1-Propyn-1-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Tetrahydro-2-Furanyl]Methyl] Ester is a high-purity, nucleoside analog derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel antiviral and anticancer therapeutics, offering researchers a reliable and well-characterized intermediate. It is essential for medicinal chemists and process development scientists working in targeted drug discovery programs, particularly those focused on nucleotide-based mechanisms.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) for hepatitis, HIV, and other viral diseases.
• Oncology Research: Serves as a building block for creating nucleotide-based chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate cellular processes and nucleotide metabolism.
• Process Chemistry & Scale-Up: Used in route scouting, optimization, and the commercial-scale manufacturing of complex active molecules.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical labs.

Basic Information

Item	Details
Product Name	Triphosphoric Acid, p-[[(2S,5R)-5-[4-Amino-5-(3-Amino-1-Propyn-1-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Tetrahydro-2-Furanyl]Methyl] Ester
CAS No.	114748-69-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7H-Pyrrolo[2,3-d]pyrimidin-7-yl tetrahydrofuran nucleoside triphosphate derivative; Amino-propyne pyrrolopyrimidine triphosphate; Nucleoside triphosphate analog; (2S,5R)-Tetrahydrofuran-2-ylmethyl triphosphate derivative; Antiviral nucleoside intermediate; 4-Amino-5-(3-aminoprop-1-yn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl tetrahydrofuran triphosphate; Research compound 114748-69-5
EINECS	Contact for details

Quality Control

Our Triphosphoric Acid derivative is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.