Description

Cyclobutanecarbonyl Chloride, 1-[(Acetyloxy)Methyl]- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride functional group and an acetyl-protected alcohol. This compound is valued for its unique cyclobutane ring structure, which is increasingly sought after in advanced pharmaceutical synthesis and materials science for its conformational rigidity and potential to modulate the properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a cyclobutane scaffold for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclobutane moiety can enhance efficacy or environmental profile.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties derived from the strained ring system.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands or organometallic catalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules to study biological pathways or develop diagnostic tools.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new chemical spaces in university and CRO laboratories.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 1-[(Acetyloxy)Methyl]- (9Ci)
CAS No.	114671-91-9
Molecular Formula	C8H11ClO3
Molecular Weight	190.62 g/mol
Synonyms	1-(Acetoxymethyl)cyclobutanecarbonyl chloride; 1-[(Acetyloxy)methyl]cyclobutanecarboxylic acid chloride; (1-(Acetoxymethyl)cyclobutyl)carbonyl chloride; Cyclobutanecarboxylic acid, 1-[(acetyloxy)methyl]-, chloride; 1-(Acetoxymethyl)cyclobutane-1-carbonyl chloride; 1-(Chlorocarbonyl)-1-(acetoxymethyl)cyclobutane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to verify identity, purity, and consistency for every batch. Certificates of Analysis (COA) detailing all critical parameters are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.