Description

21-(6-Hydroxy-1-Oxohexyloxy)-11β,17-Dihydroxypregna-4-Ene-3,20-Dione is a high-purity synthetic steroid derivative, specifically a 21-ester of a key corticosteroid intermediate. This compound matters as a critical building block in the pharmaceutical synthesis of advanced steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of novel corticosteroid drugs, anti-inflammatory agents, and other specialized therapeutic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of potent corticosteroid APIs.
• Research & Development: Used in medicinal chemistry research for the design and synthesis of new steroid-based drug candidates with modified pharmacological profiles.
• Anti-inflammatory Agent Synthesis: A crucial building block for manufacturing advanced glucocorticoids with targeted anti-inflammatory and immunosuppressive activities.
• Reference Standard: Can be utilized as a high-purity analytical reference standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and process optimization studies for the commercial production of steroid pharmaceuticals.

Basic Information

Product Name	21-(6-Hydroxy-1-Oxohexyloxy)-11β,17-Dihydroxypregna-4-Ene-3,20-Dione
CAS No.	114593-88-3
Molecular Formula	C27H38O7
Molecular Weight	474.59 g/mol
Synonyms	21-(6-Hydroxy-1-oxohexyloxy)-11β,17-dihydroxypregn-4-ene-3,20-dione; 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 21-(6-hydroxycaproate); 21-(6-Hydroxycaproyloxy)-11β,17-dihydroxypregn-4-ene-3,20-dione; Prednisolone 21-(6-hydroxyhexanoate); 11β,17-Dihydroxy-21-(6-hydroxy-1-oxohexyloxy)pregn-4-ene-3,20-dione; Steroid intermediate 114593-88-3
EINECS	Contact for details

Quality Control

Our 21-(6-Hydroxy-1-Oxohexyloxy)-11β,17-Dihydroxypregna-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.