Description

5,6-Dihydro-5-Aza-2'-Deoxycytidine is a chemically modified nucleoside analog of deoxycytidine, where a nitrogen atom replaces a carbon in the cytosine base. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of antiviral and anticancer agents, as well as in epigenetic research and diagnostic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Epigenetics Research: Used as a tool compound in studies involving DNA methylation and gene expression regulation.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for various nucleoside-metabolizing enzymes.
• Diagnostic Reagent Development: Acts as a component in the development of diagnostic kits and assays for genetic and viral testing.
• Antiviral Agent Development: Investigated for its potential activity against a range of viral pathogens.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in laboratories.

Basic Information

Product Name	5,6-Dihydro-5-Aza-2'-Deoxycytidine
CAS No.	114522-16-6
Molecular Formula	C8H12N4O4
Molecular Weight	228.21 g/mol
Synonyms	5,6-Dihydro-5-aza-2'-deoxycytidine; 5-Aza-5,6-dihydro-2'-deoxycytidine; 2'-Deoxy-5,6-dihydro-5-azacytidine; Dihydro-5-aza-2'-deoxycytidine; 5,6-Dihydro-5-azadeoxycytidine; NSC 264880; 5-Aza-dC-dihydro; 5,6-Dihydro-5-aza-dC
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-5-Aza-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.