Description

Phenelfamycin E is a specialized macrolide antibiotic belonging to the elfamycin class, known for its potent activity against Gram-positive bacteria. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying novel antibacterial agents and resistance mechanisms. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and veterinary medicine sectors who require high-purity bioactive compounds for advanced therapeutic applications.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibacterial drugs.
• Microbiological Studies: Used in academic and industrial laboratories to investigate bacterial protein synthesis inhibition, antibiotic mechanisms of action, and the emergence of resistance.
• Veterinary Medicine: Potential application in the formulation of antimicrobial treatments for livestock and companion animals.
• Biochemical Assay Development: Employed as a critical reagent in high-throughput screening (HTS) assays to discover new antimicrobial compounds or adjuvants.
• Quality Control & Regulatory Compliance: Acts as a certified reference material (CRM) for the quality assurance and analytical testing of related antibiotic products.

Basic Information

Product Name	Phenelfamycin E
CAS No.	114451-31-9
Molecular Formula	C40H61NO14
Molecular Weight	779.91 g/mol
Synonyms	Phenelfamycin E; Antibiotic A 35512B; A-35512 B; L 17046; (3R,4S,5S,6R,8R,9R,10E,12E,15R)-4-[(2S,3S,4S,5S,6R)-4,5-Dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]oxy-15-[(2R,3R,4S,5S,6R)-4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl]oxy-5,9,13-trimethyl-6-prop-1-en-2-yl-1-oxacyclopentadeca-10,12-diene-3,8-dione
EINECS	Contact for details

Quality Control

Every batch of Phenelfamycin E is manufactured and tested under strict quality management systems to ensure identity, purity, and potency. Our analytical methods, including HPLC and spectroscopic techniques, are validated to meet the rigorous standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.